Systematic expression analysis of ligand-receptor pairs reveals important cell-to-cell interactions inside glioma
Abstract Background Glioma is the most commonly diagnosed malignant and aggressive brain cancer in adults.Traditional researches mainly explored the expression profile of glioma at cell-population level, but ignored the heterogeneity and interactions of among glioma cells.Methods Here, we firstly analyzed the single-cell RNA-seq (scRNA-seq) data of